Kerala Journal of Ophthalmology

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 28  |  Issue : 2  |  Page : 116--119

Myopic choroidal neovascular membrane: A retrospective study


S Sindhu, G Mahesh, Bindu Rajesh, A Giridhar 
 Department of Vitreoretinal Services, Giridhar Eye Institute, Kochi, Kerala, India

Correspondence Address:
S Sindhu
Fellow National Board (Vitreoretinal Surgery), Giridhar Eye Institute, Kadavathara, Kochi, Kerala
India

Purpose: The purpose of the study was to analyse the fundus fluorescein angiographic (FFA) and Spectral domain Optical coherence tomographic (SD- OCT) patterns of myopic CNVM and to evaluate their response to anti-VEGF. Materials and Methods: This is a retrospective analysis of 24 treatment naïve eyes diagnosed with myopic CNVM. Eyes with age related macular degeneration, coexisting diabetes mellitus, inflammatory CNVM, idiopathic CNVM and Pseudophakia were excluded.Analysis of degree of myopia, the best corrected visual acuity (BCVA) at presentation and one year after treatment, FFA features, SD-OCT images and the response to intravitreal anti VEGF injections were carried out. Results: 24 eyes of 21patients ( 6 males, 15 females) were included in the study Mean age of the patients was 44.78 ± 17.40 years.Degree of myopia ranged from -2.5D to -22 D. Fundus fluorescein angiography showed classic CNVM in all eyes with subfoveal location in 19 eyes and juxtafoveal in 5 eyes. SD-OCT imaging showed subretinal hyperreflective material with intraretinal oedema in all eyes. Intravitreal bevacizumab (1.25mg in 0.5ml) was given in 18 eyes and ranibizumab (0.5 mg in 0.5ml) in 6 eyes. Mean number of injections taken was 1.83 (range 1 to 5). At 1 year follow up,13 eyes showed improvement in BCVA (54.16%), 6 worsened (25%), 5 remained stable (20.83%). Conclusion: Myopic CNVM responds to finite number of anti-VEGF injections anatomically and visually with no associated complications. The worsening is due to degenerative changes rather than recurrence of CNVM.


How to cite this article:
Sindhu S, Mahesh G, Rajesh B, Giridhar A. Myopic choroidal neovascular membrane: A retrospective study.Kerala J Ophthalmol 2016;28:116-119


How to cite this URL:
Sindhu S, Mahesh G, Rajesh B, Giridhar A. Myopic choroidal neovascular membrane: A retrospective study. Kerala J Ophthalmol [serial online] 2016 [cited 2019 Dec 13 ];28:116-119
Available from: http://www.kjophthal.com/article.asp?issn=0976-6677;year=2016;volume=28;issue=2;spage=116;epage=119;aulast=Sindhu;type=0