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Year : 2020  |  Volume : 32  |  Issue : 1  |  Page : 51-55

Microbial profile of lid margin flora in anterior blepharitis as compared with normal: A comparative, descriptive study

Department of Ophthalmology, Amala Institute of Medical Sciences, Thrissur, Kerala, India

Correspondence Address:
Dr. Merie Mathew
Pazhampillil (H), Kummanode, Pattimattom (PO), Ernakulam - 683 562, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/kjo.kjo_9_20

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Context: Blepharitis is a condition that causes inflammation of the eyelids, and identification of the common bacterial pathogens along with its antibiotic susceptibility pattern is essential. Aims: The aim of this study is to identify the lid margin flora in a cohort with anterior blepharitis and to compare the microbiological profile with age-matched controls and determine the antibiotic sensitivity pattern of the flora identified. Settings and Design: A comparative, descriptive study was conducted in the Department of Ophthalmology, Amala Institute of Medical Sciences, Thrissur, Kerala, India, over a period of 18 months. Subjects and Methods: The specimen for the microbial study was collected from the concerned eyelids. Smear was prepared, and primary culturing was done to identify the organism, and antibiotic susceptibility testing was performed. Statistical Analysis Used: Statistical Package for the Social Sciences software (version 23) Amala Institute of Medical Sciences, (Thrissur) was used for the statistical analysis. Results: The predominant age group of cases was 40–60 years, with a female preponderance. The bacteria isolated from cases in the order of decreasing frequency were coagulase-negativeStaphylococcus aureus(CoNS) (40.74%), coagulase-positive S. aureus (35.18%), methicillin-resistant Staphylococcus aureus(MRSA) (9.25%), and diphtheroids (5.55%) and were comparable with controls. MRSA and parasites were exclusively isolated from the cases. CoNS was highly sensitive to tetracycline (87.5%), gentamicin (87.5%), and chloramphenicol (85.4%). S. aureus was sensitive to chloramphenicol (95.1%), clindamycin (87.8%), and tetracycline (85.4%). MRSA was 100% sensitive to vancomycin and linezolid. Conclusions: Microbes identified in cases were comparable with that of controls. CoNS was the most common isolate followed by coagulase-positive S. aureus. They both showed high sensitivity to chloramphenicol and tetracycline but were resistant to penicillin. MRSA was sensitive to vancomycin and linezolid.

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