|LETTER TO EDITOR
|Year : 2017 | Volume
| Issue : 3 | Page : 256
Reply: Pigmented ocular surface squamous neoplasia
Philip Kuruvilla, Ashish George Kuruvilla
Anterior Segment Services, Aradhana Eye Institute, Thiruvananthapuram, Kerala, India
|Date of Web Publication||30-Jan-2018|
Anterior Segment Services, Aradhana Eye Institute, Thiruvananthapuram, Kerala
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Kuruvilla P, Kuruvilla AG. Reply: Pigmented ocular surface squamous neoplasia. Kerala J Ophthalmol 2017;29:256
We thank Drs. Chauhan and Sharma for their interest in our article. We agree with all the additional points which they have meticulously mentioned toward working up of a case of malignant ocular surface squamous neoplasia (OSSN).
We accept that all the negative findings on history and examination pertaining to the topic of concern were not included in the manuscript though undertaken. The decision to exclude certain investigations or to highlight certain positive findings was largely based on the extent of relevance in dealing with the specific case at hand.
Ultraviolet (UV) rays have undoubtedly been a strong risk factor in developing OSSN.,, Older age group (average 56 years), male sex, and geographic location closer to the equator (with regard to ambient solar UV-B radiation) are documented risk factors which are all the more significant when combined together., Our patient was a 58-year-old healthy Indian male, working long hours outdoors in a middle Eastern country, with a limbal lesion in the sun-exposed interpalpebral area. This, in addition to the negative history of high-risk behavior in this patient, prompted us not to test for HIV at the time. The dermatological examination was done and was unremarkable.
The case we presented was a carcinoma in situ (conjunctival intraepithelial neoplasia III), a form of preinvasive OSSN, in which dysplastic cells are restricted up to the basement membrane of the epithelium. The substantia propria in these cases is free of tumor, therefore, eliminating the risk of metastasis. Had this been an invasive squamous cell carcinoma, further investigations would have been deemed necessary.
Financial support and sponsorship
This study was financially supported by Aradhana Eye Institute, Thiruvananthapuram, Kerala, India.
Conflicts of interest
There are no conflicts of interest.
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