|LETTER TO EDITOR
|Year : 2017 | Volume
| Issue : 3 | Page : 255
Ocular surface squamous neoplasia: Missing links
Anubhav Chauhan, Shveta Chauhan
Department of Ophthalmology, Dr. Yashwant Singh Parmar Government Medical College, Sirmaur District, Himachal Pradesh, India
|Date of Web Publication||30-Jan-2018|
Department of Ophthalmology, Dr. Yashwant Singh Parmar Government Medical College, Sirmaur District, Himachal Pradesh
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Chauhan A, Chauhan S. Ocular surface squamous neoplasia: Missing links. Kerala J Ophthalmol 2017;29:255
Diagnosing and treating a rare case of ocular surface squamous neoplasia (OSSN) has been brilliantly described by Kuruvilla and Kuruvilla, and we applaud the authors for their hard work. Some very important and interesting points need a special mention while dealing with cases of OSSN.
Rule of 75 applies to this disease. About 75% of OSSN occurs in men, 75% are diagnosed in older patients, and 75% occur at the limbus. Besides ultraviolet light and human papilloma virus, other etiological agents implicated are smoking, genetic defects as in xeroderma pigmentosum, atopic eczema, pemphigoid, immunosuppressive conditions, such as human immunodeficiency virus (HIV), eye injury, petroleum products, arsenic, Vitamin A deficiency, and chronic blepharoconjunctivitis. These tumors rarely metastasize though intraocular, intraorbital, and distant metastasis has been reported.
Hence, a meticulous history plus an HIV test and a complete dental and dermatological examination should have been carried out in this case. Second, radiological investigations of the brain, orbit, chest, and abdomen should be conducted to rule out any metastasis.
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Conflicts of interest
There are no conflicts of interest.
| References|| |
Kuruvilla P, Kuruvilla A. Pigmented ocular surface squamous neoplasia. Kerala J Ophthalmol 2017;29:51-3. [Full text]
Chauhan A, Sharma SD. Squamous cell carcinoma of the conjunctiva: A rare case report. Clin Cancer Investig J 2016;5:460-2. [Full text]