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 Table of Contents  
LETTER TO EDITOR
Year : 2017  |  Volume : 29  |  Issue : 3  |  Page : 255

Ocular surface squamous neoplasia: Missing links


Department of Ophthalmology, Dr. Yashwant Singh Parmar Government Medical College, Sirmaur District, Himachal Pradesh, India

Date of Web Publication30-Jan-2018

Correspondence Address:
Anubhav Chauhan
Department of Ophthalmology, Dr. Yashwant Singh Parmar Government Medical College, Sirmaur District, Himachal Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/kjo.kjo_89_17

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How to cite this article:
Chauhan A, Chauhan S. Ocular surface squamous neoplasia: Missing links. Kerala J Ophthalmol 2017;29:255

How to cite this URL:
Chauhan A, Chauhan S. Ocular surface squamous neoplasia: Missing links. Kerala J Ophthalmol [serial online] 2017 [cited 2018 Sep 19];29:255. Available from: http://www.kjophthal.com/text.asp?2017/29/3/255/224301



Dear Sir,

Diagnosing and treating a rare case of ocular surface squamous neoplasia (OSSN) has been brilliantly described by Kuruvilla and Kuruvilla,[1] and we applaud the authors for their hard work. Some very important and interesting points need a special mention while dealing with cases of OSSN.

Rule of 75 applies to this disease. About 75% of OSSN occurs in men, 75% are diagnosed in older patients, and 75% occur at the limbus. Besides ultraviolet light and human papilloma virus, other etiological agents implicated are smoking, genetic defects as in xeroderma pigmentosum, atopic eczema, pemphigoid, immunosuppressive conditions, such as human immunodeficiency virus (HIV), eye injury, petroleum products, arsenic, Vitamin A deficiency, and chronic blepharoconjunctivitis. These tumors rarely metastasize though intraocular, intraorbital, and distant metastasis has been reported.[2]

Hence, a meticulous history plus an HIV test and a complete dental and dermatological examination should have been carried out in this case. Second, radiological investigations of the brain, orbit, chest, and abdomen should be conducted to rule out any metastasis.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Kuruvilla P, Kuruvilla A. Pigmented ocular surface squamous neoplasia. Kerala J Ophthalmol 2017;29:51-3.  Back to cited text no. 1
  [Full text]  
2.
Chauhan A, Sharma SD. Squamous cell carcinoma of the conjunctiva: A rare case report. Clin Cancer Investig J 2016;5:460-2.  Back to cited text no. 2
  [Full text]  




 

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